Any need to revisit the male reproductive toxicity of lead?

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Any need to revisit the male reproductive toxicity of lead?

T he toxicity of lead has been known for millennia and has served as a template for toxicology studies. According to some 45 000 measurements in European industrial settings spanning smelters, battery manufacturing, and foundries, the average concentration of lead in blood steadily declined from 68 mg/dl in 1970 to 35 mg/dl in 1995. In parallel with this development the introduction of non-lead...

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P-43: Reproductive Toxicity of Low Metal Exposureon Male

Background: Recent evidence has indicated a deterioration in reproductive health of men in many countries over the past few decades, particularly a decrease in semen quality and an increase in prevalence of prostate cancer. The human male has a relatively low fertility potential as compared to other mammals. Thus, the human male may be at greater risk from reproductive toxicants. For example, t...

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P-38: Protective Effects of Dorema Aucheri (Bilhar) Against Lead Acetate-Induced Reproductive Toxicity in Male Rats

most serious problem that leads to reproductive system failure in both human and animals. Present study was carried out to investigate whether hydroalcholic extract of Dorema aucheri leaves could protect the male rats against lead-induced reproductive toxicity. Materials and Methods: Adult wistar rats were treated with 0.1% lead acetate in drinking water with or without 100, 200 and 400 mg/kg D...

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Male reproductive toxicity of lead in animals and humans. ASCLEPIOS Study Group.

OBJECTIVE To critically review the literature on male reproductive toxicity of lead in animals and humans. METHODS A systematic literature search identified a total of 32 experimental studies in animals and 22 epidemiological studies, one case report on humans and five review articles or documents. The studies were evaluated by paying attention mainly to sample size, study design, exposure, a...

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ژورنال

عنوان ژورنال: Occupational and Environmental Medicine

سال: 2005

ISSN: 1351-0711

DOI: 10.1136/oem.2004.016543